Oxytocic Agents

Oxytocic Action of Neptal

The cardiovascular effects of oxytocic drugs.

The effects of ergometrine 0.5 mg i.v. and of synthetic oxytocin 5 units i.v. on the alpha and the beta adrenoceptive blood vessels of the foreann have been studied by means of volume-pulse plethysmography in 40 gynaecological patients. Ergometrine constricted the alpha and the beta blood vessels. It is thought that the widespread vasoconstriction may precipitate post-partum hypertension or pul...

Ergot of Rye as an Oxytocic

tioners were frequently in the habit of giving it to hasten tedious labour that was occasioned solely by the presence of some mechanical obstacle. In this way they invoked and called to their aid the powers, as Dr. Barnes has remarked, of a Frankenstein, quite beyond their control, whose unbridled strength might give rise to frightful disasters; in their ignorance they quite forgot that the pro...

Partial separation of an oxytocic principle from preparations of angiotonin.

A THE name implies, angiotonin is characterized by its action on vascular smooth muscle. This activity is usually assayed from its pressor effect in intact animals. Preparations of angiotonin have also been observed to cause contraction of nonvascular smooth muscle and, on this basis, the pressor activity of angiotonin has been attributed to a direct myotropic action of a single substance' ; th...

Release of an oxytocic substance following genital stimulation in bulls.

The oxytocic activity of the jugular blood plasma of bulls before and after copulation, ejaculation into an artificial vagina, massage of the seminal vesicles and ampullae and stimulation with an electroejaculator increased from below 0\m=.\01\g=m\U/mlto a peak level varying from 2 to 1000 \g=m\U/ml4 to 6 min after ejaculation or 6 to 9 min after the start of electrical or manual stimulation.